Peachtree City, Georgia
Relief is possible, even when you’ve tried everything else.
Breakthrough Therapeutics offers outpatient, medically supervised ketamine treatment for depression, anxiety, and PTSD, delivered with warmth, safety, and careful clinical monitoring.
Where your healing journey unfolds
You are not out of options
If standard antidepressants haven’t worked, you’re not alone, and you’re not stuck. Roughly one in three people with depression don’t find relief from conventional medication.1 Ketamine works through a different pathway in the brain, and for many people it brings relief in days rather than weeks.2
The basics
What is ketamine therapy?
Ketamine is a non-opioid medication that has been used in operating rooms and emergency departments for more than 50 years.3 It is commonly used to provide sedation and pain relief during procedures such as fracture reduction in children because it generally preserves spontaneous breathing and protective airway reflexes.
At low, sub-anesthetic doses, ketamine affects the brain’s glutamate system, a different target from traditional antidepressants. Research suggests that it promotes neuroplasticity and helps strengthen or form new connections between brain cells.2
Although ketamine is not FDA-approved for depression, it has been evaluated in more than 50 clinical studies, with additional research ongoing. The evidence supports its rapid, short-term effectiveness and favorable safety profile when administered under medical supervision. This use is considered off-label, meaning an established medication is prescribed for a purpose beyond its FDA-approved indication, a common and legally permitted practice in medicine.

The evidence
How well does ketamine work?
Results are based on published clinical studies and do not guarantee individual outcomes.
How we can help
Conditions ketamine may help
We treat adults whose symptoms haven’t responded fully to other approaches. A thorough evaluation determines whether treatment is right for you.
Difficult-to-treat depression
Depression that hasn’t responded to two or more antidepressants, the most studied use of ketamine.4
Major depressive disorder
Persistent low mood, loss of interest, and fatigue that interfere with daily life.
PTSD
Trauma-related symptoms, evaluated individually for suitability.
Why people consider ketamine
Fast-acting, when time matters most
Unlike traditional antidepressants that can take four to twelve weeks, ketamine’s effects often appear quickly. Here’s what the research shows.
The experience
What your journey looks like
Healing unfolds in stages. We walk beside you through each one.
Consultation
A thorough review of your history and goals to confirm ketamine is a safe, appropriate fit.
Preparation
We explain what to expect and help you settle into a calm, supported mindset before treatment.
Treatment
A sub-anesthetic dose is administered on-site while we monitor you closely in a comfortable space.
Integration
We help you reflect on the experience and track your progress between sessions.

Safe, supervised care
You’re in experienced hands
Each treatment is administered by a board-certified physician assistant with emergency medicine experience and advanced ketamine training, in collaboration with our physician Medical Director. Your provider remains present throughout the session, providing continuous monitoring and individualized care.
- Medically supervised, sub-anesthetic dosing
- Continuous monitoring throughout treatment
- Comprehensive medical and mental health screening
- Optional ketamine-assisted psychotherapy (KAP) with an experienced KAP-certified therapist
An honest word
Is ketamine right for you?
We believe in clear, honest information, not hype. Here’s what to keep in mind:
- Ketamine is a treatment, not a cure. In real-world use, a meaningful share of people with difficult-to-treat depression do not improve, and results vary by person.6
- It works best as part of a broader care plan, often alongside therapy and ongoing support.
- A medical and psychological evaluation is required to determine whether it’s safe and appropriate for you.
- It is not emergency care. If you’re in crisis, call or text 988 (Suicide & Crisis Lifeline) or 911.
Questions
Frequently asked
Does ketamine therapy hurt?
You’ll feel a small pinch when the IV is placed, but the treatment itself isn’t painful. Some people feel temporarily dreamy or “floaty,” which fades after the session. You’re monitored the whole time.
What does it feel like?
At the doses we use, ketamine can create a temporary dreamlike or “dissociative” feeling of being detached from your body or surroundings. It’s expected and it fades as the medicine wears off. A member of our clinical team is with you throughout. More on what to expect →
How quickly might I feel a difference?
Many people notice changes within hours to days, faster than traditional antidepressants, which can take weeks.2 Everyone responds differently, which is why we track your progress closely.
Do you accept insurance?
Breakthrough Therapeutics is a self-pay practice. Insurance plans do not cover ketamine treatment for mental health conditions, so payment is handled directly at the time of service.
Where are you located?
6000 Shakerag Hill, Suite 314, Peachtree City, GA 30269
Take the first step
Your healing journey can start today
Reach out for a confidential consultation. We’ll listen, answer your questions, and help you decide what’s right for you, no pressure.